教師著作目錄-資料表PERSONAL DATA
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單位: 獸醫學院 獸醫學系 教師姓名: 張天傑 職稱: 教授兼副校長 Name: CHANG, TIEN-JYE E-mail: tjchang@dragon.nchu.edu.tw TEL:886-4-2284-0894 ext 309 FAX:886-4-22852658 最高學位: 美國加州大學戴維斯校博士 |
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學歷
台北市立建國高級中學畢業 專長
病毒學,免疫學,生物科技 |
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簡要經歷: 國立中興大學獸醫學系講師 (1978. 12 – 1987. 7) 國立中興大學獸醫學系副教授 (1987. 8 – 1992. 7) 國立中興大學獸醫學系教授 (1992. 8 – 迄今) 國立中興大學農學院附設家畜醫院檢驗科主任 (1988. 8 – 1994. 7) 國立中興大學動物學系第一任系主任 (1994. 9 – 1997. 7) 國立中興大學獸醫學系系主任 (1999. 8 – 2000. 8 ) 台中市龍邦綠園道社區管理委員會第二屆主任委員 (1994. 10 – 1996. 1) 台中市大博士公寓大廈管理委員會第一屆主任委員 (1998. 7 – 1999. 6) 國立大里高級中學家長會會長 (2001. 9 – 2003. 8) 農委會動植物防疫檢疫局防檢疫審議委員會委員 (1995. 8 – 迄今) 農委會動植物防疫檢疫局動物用藥品技術審議委員會委員 (1996. 8 – 迄今) 農委會動植物防疫檢疫局豬瘟及口蹄疫撲滅計畫因應小組委員 (1999. 8 – 迄今) 行政院國家科學委員會畜牧獸醫學門召集人 (2003. 1 – 2004. 12) 行政院農業委員會農業科技發展策略規劃委員會委員 (2003. 4 – 2003. 9) 台灣畜牧獸醫學會理事長 (2001. 2 – 2004. 1及2005. 2 – 迄今) 中華民國獸醫學會理事長 (2005. 2 – 迄今) 台中市獸醫師公會顧問 (2004. 1 – 迄今) 中華民國獸醫師公會聯合會顧問 (2005. 4 – 2008. 3) 財團法人李崇道基金會董事 (2002. 8 – 迄今) 中華民國養豬事業發展協進會顧問 (2001. 3 – 迄今) 財團法人動物科技研究所顧問 (2003.1 – 2005.12) 台灣農業產學聯盟秘書長 (2004. 5 – 2008. 4) 農委會大熊貓輸入案專案審查小組委員 (2005. 12 – 2006. 4) 實驗動物資源體系跨部會工作小組委員 (2005.1 – 迄今) 世界動物衛生組織中華民國常任代表 (2003. 8 – 迄今) (OIE, Office International Des Epizooties) (World Organization for Animal Health) 世界動物衛生組織亞太區副主席 (2006. 6 – 迄今) 國立中興大學獸醫學院院長 (2000. 8 – 2006. 7) 國立中興大學副校長 (2006. 8 – 迄今)
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專長: 病毒學 免疫學 生物技術 獸醫預防醫學 |
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研究領域: 分子病毒致病機制 動物疫苗及診斷試劑 生物技術 獸醫預防醫學
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研究興趣: 主要在分子病毒學、病毒感染的致病機轉、及病毒感染所造成之免疫反應等方面。目前從事豬假性狂犬病毒與豬瘟病毒之分子病毒學研究,尤其是假性狂犬病毒基因調節及病毒基因表現與細胞互動關係的研究等。同時,亦進行豬多價標識疫苗及鑑別診斷試劑之研究。
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主要教授課程(含大學部及研究所): 大學部:獸醫病毒學,獸醫預防醫學,動物病毒學 研究所:分子病毒學,分子免疫學,動物病毒學文獻探討,單源抗體技術學
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最近參與的研究計劃案: 豬瘟病毒之分子生物學研究(國科會計劃88-91) 假性狂犬病毒立即早期基因與vhs基因調控之機轉之研究(國科會計劃90-92) 豬多價標識疫苗之研發(農委會計劃90-92) 豬病毒性疾病快速診斷鑑定技術標準流程之建立(農委會計劃90) 以螢光標示融合蛋白鑑別診斷豬瘟抗體之研究(農委會計劃91)
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(A) Referred Papers 1. Pritchett[1]*, R. F., C. E. Bush, T.-J. Chang, J. T. Wang, and Y. C. Zee. 1984. Comparison of the genomes of pseudorabies (Aujeszky's disease) virus strains by restriction endonuclease analysis. Am. J. Vet. Res. 45, 2486-2489. (SCI) 2. Chang*, T.-C., T.-J. Chang, Y.-S. Huang, C.-C. Chang, and F.- W. Chen. 1987. Adenylate cyclase system of porcine salivary gland and its relationship to thyrotropin. J. Formosan Med. Assoc. 86, 1245-1250. (SCI) 3. Lee*, W.-C., T.-J. Chang, J.-T. Wang, and L.-J. Leu. 1989. Investigation of maternal antibody against pseudorabies virus in progeny of the immunized sows. J. Chinese Soc. Vet. Sci., 15:27-32. 4. Chang*, T.-J., T.-M. Chou, and J.-T. Wang. 1989. The development and identification of a defective thymidine kinase induced activity mutant of pseudorabies virus. J. Chinese Soc. Vet. Sci., 15:185-191. 5. Chang*, T.-J., W.-C. Lee, J.-T. Wang and L.-J. Leu. 1989. Antibody prevalence and virus shedding on two Taiwan pig farms with acute pseudorabies infection. J. Chinese Soc. Vet. Sci., 15:301-307. 6. Lee*, W.-C., T.-J. Chang, C.-C. Lee, J.-T. Wang, J.-H Shen, L.-J. Leu. 1989. The immune response to pseudorabies inactivated vaccines in weaned piglets on pseudorabies virus- infected farms. J. Chinese Soc. Vet. Sci. 15:309-316. 7. Chang*, T.-J., C.-J. Huang, J.-T. Wang. 1989. Production and utilization of monoclonal antibody against pseudorabies virus. Taiwan Jour. Vet. Med. & Anim. Husb., 53:17-26. 8. Chang*, T.-C., J.-J. Lin, S.-C. Yu, and T.-J. Chang. 1990. Absence of growth hormone receptor in hepatocellular carcinoma and cirrhotic liver. Hepatology. 11:123-126. (SCI) 9. Chang*, T.-C., K.-M. Huang, T.-J. Chang, and S.-L. Lin. 1990. Correlation of orbital computed tomography and antibodies in patients of hyperthyroid Graves' disease. Clinical Endocrinology., 32:551-558. (SCI) 10. Chang*, T.-J. 1991. Detection of pseudorabies virus genetic sequences by polymerase chain reaction. Taiwan Jour. Vet. Med. & Anim. Husb., 57:1-17. 11. Chang*, T.-J. and W.-C. Lee. 1991. Utilization of direct immunoperoxidase method to detect pseudorabies virus dissemination in infected pigs. Taiwan Jour. Vet. Med. & Anim. Husb., 58:17-26. 12. Chang*, T.-C., T.-J. Chang, Y.-S. Huang, K.-M. Huang, R.-J. Su, and S. C. S. Kao. 1992. Identification of autoantigen recognized by autoimmune ophthalmopathy sera with immunoblotting correlated with orbital computed tomography. Clin. Immuno. & Immunopath. 65, 161-166. 13. Chang*, T.-J., T.-S. Huang, W.-C. Ho, and Y.-H. Yang. 1993. A serological survey of pseudorabies among finishing pigs in Taiwan from 1987 to 1991. J. Chin. Soc. Vet. Sci. 19, 19-25. 14. Chung, Y.-T., T.-Y. Chang, T.-J. Chang*, and F. Wu. 1993. Detection of infectious bovine rhinotracheitis virus DNA by the nested double polymerase chain reaction method. J. Chin. Soc. Vet. Sci. 19, 26-37. 15. Chang*, T.-C., S.-L. Wu, Y.-L. Hsiao, S.-H. Kao, L.-F. Chien, Y.-F. Kuo, C.-C. Chang, and T.-J. Chang. 1994. TSH and TSH receptor antibody-binding sites in fibroblasts of pretibial myxedema are related to the extracellular domain of entire TSH receptor. Clin. Immuno. & Immunopath. 71, 113-120. (SCI) 16. Wong*, M.-L., T.-J. Chang, and C.-Y. Wang. 1995. Short communication: one step filtration method for isolation of herpesviral DNA. Taiwan J. Vet. Med. Anim. Husb. 65, 189-192. 17. Wong, M.-L., S.-T. Kuo and T.-J. Chang*. 1995. Cloning and sequencing of glycoprotin H gene of the pseudorabies virus strain TNL. Taiwan J. Vet Med. Anim. Husb. 65, 317-325. 18. Ho, T.-Y., C.-Y. Hsiang, S.-L. Wu and T.-J. Chang*. 1995. Cloning and analysis of pseudorabies virus replication-independent transcripts. J. Chin. Soc. Vet. Sci. 21(4), 201-211. (in chinese). 19. Chung, Y.-T., W.-J. Du, and T.-J. Chang*. 1995. Restriction endonuclease analysis of the genomes of pseudorabies virus strains isolated in Taiwan. Taiwan J. Vet. Med. Anim. Husb. 65, 11-20. 20. Chung*, Y.-T., L.-J. Wang, and T.-J. Chang. 1995. Structure analysis of the gene encoding the pseudorabies virus (Taiwan TNL strain) glycoprotein gp50. Taiwan J. Vet. Med. Anim. Husb. 65, 119-130. 21. Hsiang, C.-Y., T.-Y. Ho, S.-L. Wu, and T.-J. Chang*. 1995. Cloning and sequencing of the ICP0 homologous gene of pseudorabies virus. J. Chin. Soc. Vet. Sci. 21(6), 327-338. 22. Wu, S.-L., T.-C. Chang*, T.-J. Chang, Y.-F. Kuo, Y.-L. Hsiao and C.-C. Chang. 1996. Cloning and sequencing of complete thyrotropin receptor transcripts in pretibial fibroblast culture cells. J. Endo. Invest., 19, 365-370. (SCI) 23. Wong, M.-L., J.-J. Liu, C. Huang, C.-M. Hsu and T.-J. Chang*. 1996. Construction and characterization of glycoprotein gE(gI) deletion mutant of pseudorabies virus strain TNL. Taiwan J. Vet. Med. Anim. Husb. 66, 235-242. 24. Hsiu, J.-S., M.-H. Chang, S.-T. Liu, W.-C. Ho, S.-S. Lai, T.-J. Chang, Y.-S. Chang*. 1996. Molecular cloning and nucleotide sequence determination of three envelope genes of classical swine fever virus Taiwan isolate p97. Virus Research, 41, 173-178. (SCI) 25. Hsiang, C.-Y., T.-Y. Ho, C.-H. Lin, K. Wu and T.-J. Chang*. 1996. Analysis of upregulated cellular genes in pseudorabies virus infection: use of mRNA differential display. J. Virol. Methods, 62, 11-19. (SCI) 26. Hsiang, C.-Y., T.-Y. Ho and T.-J. Chang*. 1996. Identification of a pseudorabies virus UL12(deoxyribonuclease) gene. Gene, 177, 109-113. (SCI) 27. Ho, T.-Y., C.-Y. Hsiang, and T.-J. Chang*. 1996. Rapid screening of the pseudorabies virus-specific cDNAs from a cDNA library. J. Virol. Methods, 58, 187-192. (SCI) 28. Ho, T.-Y., C.-Y. Hsiang, and T.-J. Chang*. 1996. Analysis of pseudorabies virus genes by cDNA sequencing. Gene, 175, 247-251. (SCI) 29. Huang*, C., Y.-S. Lin, J.-W. Cheng, and T.-J. Chang. 1997. Immunolocalization of the pseudorabies virus immediate-early protein IE180 by immunoperoxidase staining. J. Virol. Methods, 66, 219-226. (SCI) 30. Wong*, M.-L., C.-Y. Wang, and T.-J. Chang. 1997. Topoisomerases are involved in the replication and gene expression of pseudorabies virus. Taiwan J. Vet. Med. Anim. Husb., 67, 61-67. 31. Wong*, M.-L., T.-Y. Ho, J.-H. Huang, C.-Y. Hsiang, and T.-J. Chang. 1997. Stimulation of type I DNA topoisomerase gene expression by pseudorabies virus. Arch. Virol. 142, 2099-2105. (SCI) 32. Shiu, J.-S., S.-T. Liu, T.-J. Chang, W.-C. Ho, S.-S. Lai, Y.-S. Chang*. 1997. The presence of RNA splicing signals in the cDNA construct of the E2 gene of classical swine fever virus affected its expression. J. Virol. Methods, 68, 223-230. (SCI) 33. Liu, J.-J., M.-L. Wong, C. Huang, and T.-J. Chang*. 1997. Serologic diagnosis of classical swine fever virus: use of recombinant antigens (core and E2) in enzyme-linked immunosorbent assays. Taiwan J. Vet. Med. Anim. Husb., 67, 127-134. 34. Liu, J.-J., M.-L. Wong, and T.-J. Chang*. 1998. The recombinant nucleocapsid protein of classical swine fever virus can act as a transcription regulator. Virus Research, 53, 75-80. (SCI) 35. Wong, M.-L., J.-J. Liu, Y.-S. Chang, and T.-J. Chang*. 1998. Expression of the glycoprotein E2 of the classical swine fever virus in Escherichia coli. J. Vet. Med. Sci. 60, 541-544. (SCI) (IF=0.434, 41/90) 36. Ho, T.-Y., C.-Y. Hsiang, C.-H. Hsiang, and T.-J. Chang*. 1998. DNA vaccination induces a long-term antibody response and protective immunity against pseudorabies virus in mice. Arch. Virol. 143, 115-125. (SCI) (IF=1.379, 11/17) 37. Hsiang, C.-Y., T.-Y. Ho, C.-H. Hsiang, and T.-J. Chang*. 1998. Recombinant pseudorabies virus DNase exhibits a RecBCD-like catalytic function. Biochem. J. 330, 55-59. (SCI) (IF=3.659, 39/173) 38. Ho, T.-Y., C.-Y. Hsiang, and T.-J. Chang*. 1998. Review: New trends in development of pseudorabies vaccines. J. Chin. Soc. Vet. Sci. 24, 1-9. (in chinese) 39. Liu, J.-J., M.-L. Wong, P.-F. Chen, and T.-J. Chang*. 1998. Cloning, expression, and sequence analysis of the classical swine fever virus nucleocapsid protein. Virus Genes, 16, 227-236. (SCI) (IF=1.412, 47/75) 40. Huang, C.-N., S.-L. Wu, T.-C. Chang*, S.-H. Huang, and T.-J. Chang. 1998. RET protooncogene mutations in patients with apparently sporadic medullary thyroid carcinoma. J. Formos. Med. Assoc., 97, 541-546. (SCI) 41. Wu, S.-L., T.-C. Chang*, C.-N. Huang, L.-M. Chuang, and T.-J. Chang. 1998. Germline RET proto-oncogene mutations in two Taiwanese families with multiple endocrine neoplasia type 2A. J. Formos. Med. Assoc., 97, 614-618. (SCI) 42. Wong, M.-L., J.-J. Liu, C. Huang, J. W. Chen, and T.-J. Chang*. 1998. Molecular cloning and nucleotide sequence of 3’-terminal region of classical swine fever virus LPC vaccine strain. Virus Genes, 17, 1-6. (SCI) (IF=1.412, 47/75) 43. Chen*, H.-C., P.-C. Chan, M.-J. Tang, C.-H. Cheng, and T.-J. Chang. 1998. Tyrosine phosphorylation of focal adhesion kinase stimulated by hepatocyte growth factor leads to mitogen-activated protein. J. Biol. Chem. 273, 25777-25782. (SCI) (IF=6.793, 15/173) 44. Wu, S.-L., C.-Y. Hsiang, T.-Y. Ho, and T.-J. Chang*. 1998. Identification, expression, and characterization of the pseudorabies virus DNA-binding protein gene and gene product. Virus Research, 56, 1-9. (SCI) 45. Wong, M.-L., C.-Y. Lin, J.-J. Liu, and T.-J. Chang*. 1998. Construction and virulence test of genetically engineered pseudorabies virus. Taiwan J. Vet. Med. Anim. Husb., 68, 1-9. 46. Ho, T.-Y., S.-L. Wu, T.-J. Chang, C.-H. Hsiang, S.-H. Chang, and C.-Y. Hsiang*. 1999. Pseudorabies virus early protein 0 trans-activates the TATA-associated promoter by stimulating the transcription initiation. Virus Research, 61, 77-86. (SCI) 47. Wu, S.-L., C.-S. L. Yang, H.-J. Wang, C.-L. Liao, T.-J. Chang, and T.-C. Chang*. 1999. Demonstration of thyrotropin receptor mRNA in orbital fat and eye muscle tissues from patients with Graves’ ophthalmopathy by in situ hybridization. J. Endo. Invest., 22, 289-295. (SCI) (IF=0.613, 74/81) 48. Chang, T.-J., S.-L. Wu, T.-C. Chang, S.-H. Huang, and T.-J. Chang. 1999. De novo ret proto-oncogene mutation in a patient with multiple endocrine neoplasia type 2B. J. Formos. Med. Assoc. 98, 692-697. (SCI) (IF=0.261, 77/100) 49. Chen*, C.-M., W. T. K. Cheng, Y.-C. Chang, T.-J. Chang, and H.-L. Chen. 2000. Growth enhancement of fowls by dietary administration of recombinant yeast cultures containing enriched growth hormone. Life Sci. 67, 2103-2115. (SCI) 50. Cheng, W. T. K., C.-H. Lee, C.-M Hung, T.-J. Chang, and C.-M. Chen*. 2000. Growth hormone gene polymorphisms and growth performance traits in Duroc, Landrace and Tao-Yuan pigs. Theriogenology, 54, 1225-1237. (SCI) 51. Liu, J.-J., M.-L. Wong, and T.-J. Chang*. 2000. DNA-binding properties of the recombinant nucleocapsid protein of classical swine fever virus. Taiwan J. Vet. Med. Anim. Husb. 70, 1-6. 52. Ho, T.-Y., S.-L. Wu, C.-H. Hsiang, T.-J. Chang, and C.-Y. Hsiang*. 2000. Identification of a DNA-binding domain and an active-site residue of pseudorabies virus Dnase. Biochem. J. 346, 441-445, Part 2 MAR 1 2000. (SCI) (IF=4.349, 53/293) 53. Wong, M.-L., B.-Y. Peng, J.-J. Liu, and T.-J. Chang*. 2001. Cloning and sequencing full length cDNA of classical swine fever virus LPC strain. Virus Genes. 23, 187-192. (SCI) (IF=1.159, 18/24) 54. Chang, Y.-Y., M.-L. Wong, H.-W. Lin, and T.-J. Chang*. 2002. Cloning and regulation of the promoter of psuedorabies virus (TNL strain) glycoprotein E gene. Virus Genes, 24, 235-242. (SCI) (IF=1.159, 18/24) 55. Huang*, C., C.-L. Lai, T.-C. Hsu, T.-J. Chang, and M.-H. Jong. 2002. Antigenic analysis of the Foot-and-month disease virus O/Taiwan/97 isolates. Taiwan Vet. J. 28, 47-54. (in Chinese) 56. Ou, C.-J., M.-L. Wong, C. Huang, and T.-J. Chang*. 2002. Suppression of promoter activity of the LAT gene by IE180 of pseudorabies virus. Virus Genes, 25, 225-237. (SCI) (IF=1.159, 18/24) 57. Ou, C.-J., M.-L. Wong, and T.-J. Chang*. 2002. A TEF-1-element is required for activation of the promoter of pseudorabies virus glycoprotein X gene by IE180. Virus Genes, 25, 239-251. (SCI) (IF=1.159, 18/24) 58. Liu*, J.-J., T.-H. Tsai, T.-J. Chang and M.-L. Wong. 2003. Cloning and sequencing of complete cDNA of Japanese encephalitis virus YL strain in Taiwan. Virus Genes, 26, 193-198. (SCI) 59. Chiou*, S.-H., J.-L. Lan, S.-L. Lin, D.-Y. Chen, N.-Y. Tsai, C.-Y. Kuan, T.-Y. Lin, F.-J. Lin, W.-M. Lee, and T.-J. Chang. 2004. Pet dogs owned by lupus patients are at a higher risk of developing lupus. Lupus. 13, 442-449. (IF=1.77, SCI) 60. Wang, H.-C., S.-H. Lee, T.-J. Chang, and M.-L. Wong*. 2004. Examination of meat components in commercial dog and cat feed by using polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLPs) technique. J. Vet. Med. Sci. 66(7), 855-859. (SCI) (IF=0.434, 41/90) 61. Chen, S.-O., T.-H. Tsai, T.-J. Chang, M.-L. Wong, H.-P. Su, and J.-J. Liu*. 2004. Expression of recombinant envelope protein of Japanese Encephalitis virus YL strain in Escherichia coli possesses hemagglutination activity. Virus Genes, 28 (2): 215-221. (SCI) 62. Chang, Y.-Y., H.-W. Lin, M.-L. Wong, and T.-J. Chang*. 2004. Regulation of the vhs gene promoter of pseudorabies virus by IE180 and EP0, and the requirement of a Sp1 site for the promoter function. Virus Genes, 28 (3): 247-258. (SCI) 63. Lin, H.-W., Y.-Y. Chang, M.-L. Wong, J.-W. Lin, and T.-J. Chang*. 2004. Functional analysis of virion host shutoff (vhs) protein of pseudorabies virus. Virology, 324(2), 412-418. (SCI) 64. Kao, Y.-C., H.-C. Wong, T.-J. Chang, and M.-L. Wong*. 2005. On the TATA box and transcriptional start site of gE gene of pseudorabies virus: a comparison of three methods. J. Virol. Methods,123, 95-99. (SCI) 65. Wang, H.-C., Y.-C. Kao, T.-J. Chang, and M.-L. Wong*. 2005. Inhibition of lytic infection of pseudorabies virus by arginine-depletion. Biochem. Biophy. Res. Commu. 334, 631-637. (SCI) 66. Chang, S.-H., C.-C. Chang, T.-J. Chang, and M.-L. Wong*. 2005. Prognostic factors associated with survival two years after surgery in dogs with malignant mammary tumors: 79 cases (1998-2002). JAVMA, 227(10), 1625-1629. (SCI) 67. Shih, H.-C., K.-B. Choo, T.-J. Chang*, M.-Y. Yang, M.-C. Shih, K.-T. Yeh, T.-C. Liu, S.-F. Lin and J.-G. Chang*. 2005. Disturbance of circadian gene expression in endometrial cancer: Detection by real-time quantitative PCR. Oncology Reports 14, 1533-1538. 68. Ke, G.-M., H.-L. Cheng, L.-Y. Ke, W.-T. Ji, Julius L. C. Chulu, M.-H. Liao, T.-J. Chang*, H.-J. Liu*. 2006. Development of a quantitative Light Cycler real-time RT-PCR for detection of avian reovirus. J. Virol. Methods. 133, 6-13. 69. Lin, W.-L., C.-J. Ou, F.-M. Huang, T.-J. Chang, and C. Huang*. 2006. Expression and characterization of the pseudorabies virus glycoprotein gH. Taiwan Vet. J., 32(1), 47-55. (in chinese) 70. Chen, S.-O., T.-J. Chang, G, Stone, C.-H. Chen, and J.-J. Liu*. 2006. Programmed cell death induced by Japanese Encephalitis virus YL vaccine strain or its recombinant envelope protein in varied cultured cells. Intervirology, 49, 346-351. (SCI)
(B) Conference Papers 1. Chang, T. J. and J. T. Wang. 1980. Neonatal immune response in pigs-early vaccination against hog cholera. Sino-Japanese Spring Meeting. May 4, 1980 in Tansui, Taiwan, ROC. 2. Wang, J. T., C. C. Sheu, T. J. Chang, W. C. Lee, Y. C. Huang, and S. S. Lai. 1980. Humoral and cellular immune response in neonatal pigs vaccinated with hog cholera vaccine. FED. ASIAN VET. ASSOC., PROCEEDINGS. SECOND CONGRESS. p. 100-102, 1980, TOKYO, 3. Wang, J. T., T. J. Chang, and C. C. Sheu. 1980. Localization of pseudorabies virus in tissues from infected pigs. INTL. PIG VET. SOC. 6TH CONG. PROCEEDINGS. p. 97, 1980 COPENHAGAN, DENMARK. 4. Wu. F. M., J. T. Wang, and T. J. Chang. 1980. Antibody contents in the colostrum from different teats in sows. INTL. PIG VET. SOC. 6TH CONG. PROCEEEDINGS. p. 187, 1980 COPENHAGAN, DENMARK. 5. Chang, T. J., R. Y. Chuang, and Y. C. Zee. 1986. Cloning the genomic RNA of the bovine viral diarrhea virus. Abstracts of the Annual Meeting of the Am. Soc. for Microb. 86th. p. 322, 1986 WASHINGTON, D. C. USA. 6. Chang, T.-J. and Y. C. Zee. 1987. Cloning the genetic sequences of bovine viral diarrhea virus. ROC-USA AGRI. BIOTECH. WORKSHOP PROCEEDINGS. pp. 145-163, 1987, TAIPEI, TAIWAN. R.O.C. 7. 張天傑,黃淑惠。1989. 豬瘟病毒基因的分子選殖。臺灣省畜牧獸醫學會七十八年度春季學術研討會。嘉義,臺灣。 8. Chang, T. J. and S. T. Lens. 1990. Detection of gX in pseudorabies virus culture supernatants of ten Taiwan isolates by enzyme-linked immunosorbent assay. INTL. PIG VET. SOC. 11TH CONG. PROCEEEDINGS. p. 240, 1990 LAUSANNE, SWITZERLAND. 9. 張天傑,張曾源。1992. 以聚合脢連鎖反應檢測牛傳染性鼻氣管炎病毒核酸。臺灣省畜牧獸醫學會八十一年度春季學術研討會。屏東,臺灣。 10. 張天傑,吳世祿。1992. 假性狂犬病毒早期基因之選殖。中華民國獸醫學會暨臺灣省畜牧獸醫學會八十一年度聯合年會學術論文發表會。台北市。 11. Chang, T. J. 1993. Detection of herpesvirus infection by polymerase chain reaction. Symposium on Application of Biotechnology for Animal Medicine. Taipei, Taiwan, R.O.C. 12. 張天傑。1993. 以聚合脢連鎖反應檢測假性狂犬病毒核酸。海峽兩岸農業生物技術產業化研討會。北京市。 13. 張天傑。1994。以聚合脢連鎖反應檢測假性狂犬病毒。海峽兩岸動植物檢疫技術研討會。上海市。1994年9月。 14. Ho, T.-Y., C.-Y. Hsiang, K. Wu, and T.-J. Chang. 1995. Rapid identification of the pseudorabies virus-specific cDNA from a substractive cDNA library. Taiwan J. Vet. Med. Anim. Husb. 65, suppl. 2, p. 32. Taichung, Taiwan。國科會計畫編號:NSC-84-2321-B-005-026。 15. Hsiang, C.-Y., T.-Y. Ho and T.-J. Chang. 1995. Identification and functional expression of pseudorabies virus alkaline deoxyribonuclease gene. Taiwan J. Vet. Med. Anim. Husb. 65, suppl. 2, p.31. Taichung, Taiwan。國科會計畫編號:NSC-84-2321-B-005-026。 16. Ho, T.-Y., C.-Y. Hsiang and T.-J. Chang. 1996. DNA requirements for transcriptional activity of pseudorabies virus. 中華民國獸醫學會暨臺灣省畜牧獸醫學會八十五年度聯合學術論文發表會。 台北市。 國科會計畫編號: NSC-85-2321-B-005-051. 17. Liu, J.-J., M.-L. Wong, and T.-J. Chang. 1996. Expression and identification of the classical swine fever virus capsid protein and its potential use as a diagnostic reagent. 中華民國獸醫學會暨臺灣省畜牧獸醫學會八十五年度聯合學術論文發表會。台北市。 18. 陳韻如,侯庭鏞,張天傑,陳震漢。1996。探索利用固定化細胞的方法培養假性狂犬病毒。 臺灣省畜牧獸醫學會八十五年度春季學術研討會。屏東市。 19. Ho, T.-Y., C.-Y. Hsiang, J.-H. Huang and T.-J. Chang. 1996. Core promoter specificities of the pseudorabies virus early protein 0. 臺灣省畜牧獸醫學會八十五年度春季學術研討會。屏東市。 20. 許晉銘,黃千衿,張天傑。1996。假性狂犬病毒雙基因缺損株R23之特性分析。 臺灣省畜牧獸醫學會八十五年度春季學術研討會。屏東市。 21. 劉昭君,張天傑,王孟亮。1997。豬瘟病毒重組核蛋白活化熱休克(Hsp70)啟動子或抑制SV40之啟動子。 臺灣省畜牧獸醫學會八十六年度春季學術研討會。台中市。 22. 朱純燕,張清華,張天傑,蕭璦莉,吳昭良。1998。豬假性狂犬病毒gE及TK基因缺損疫苗之研發。八十六年度臺灣省畜牧獸醫學會暨中華民國獸醫學會聯合學術研討會。台中市。 23. Chiu, H.-Y., T.-J. Chang, and M.-L. Wong. 1999. Actin-binding protein in pseudorabies virus-infected cells. 八十八年度臺灣省畜牧獸醫學會暨中華民國獸醫學會聯合學術研討會。台中市。 24. Chang, Y.-Y., J.-J. Liu, M.-L. Wong, H.-Y. Chiu, and T.-J. Chang. 1999. Recombinant structural protein of classical swine fever virus as a differential diagnostic reagent. 八十八年度臺灣省畜牧獸醫學會暨中華民國獸醫學會聯合學術研討會。台中市。 25. Chang, Y.-Y., J.-J. Liu, M.-L. Wong, H.-Y. Chiu, W.-C. Lee, C.-J. Huang, M.-H. Jong, T.-J. Chang. 2000. A novel modified ELISA for detecting recombinant core and glycoprotein E2 in classical swine fever virus. The 11th Congress of the Federation of Asian Veterinary Associations. Taipei, Taiwan. November 27, 2000. 26. Ou, C.-J., Y.-H. Chen, T.-J. Chang, C.-J. Huang. 2000. Cloning and analysis of the pseudorabies virus (TNL strain) latency-associated transcript promoter. The 11th Congress of the Federation of Asian Veterinary Associations. Taipei, Taiwan. November 27, 2000. 27. Chang, Y.-Y., M.-L. Wong, H-W Lin, and T.-J. Chang. 2000. Cloning and regulation of the promoter of pseudorabies virus glycoprotein E. Eighth Symposium on Recent Advances in Cellular and Molecular Biology. Kenting, Pintung. 28. Ou, C.-J., M.-L. Wong, C.-J. Huang, T.-J. Chang. 2001. Effects of the pseudorabies virus immediate-early protein during lytic and latent infection. The 15th Joint Annual Conference of Biomedical Science. Taipei, Taiwan. 29. 李國豪,劉昭君,張天傑,王孟亮。2001。以大腸桿菌表現結構蛋白-螢光素融合蛋白偵測豬瘟抗體之研究。臺灣省畜牧獸醫學會九十年度春季學術研討會。屏東縣。中華民國九十年五月十九日。 30. 張天傑。2001。以大腸桿菌表現蛋白偵測豬瘟抗體之研究。海峽兩岸動植物防疫檢疫研討會。中國大陸北京市。 31. 林惠雯、王孟亮、張元衍、及張天傑. 2002. 假性狂犬病毒UL41(vhs)基因的選殖、表現、及功能分析。九十一年度臺灣省畜牧獸醫學會春季學術研討會。台中市。P16. May 17, 2002. 32. Wu, P.-Y., M.-L. Wong, and T.-J. Chang. 2002. Construction of full-length pseudorabies virus TNL genome as the bacterial artificial chromosome. 九十一年度臺灣省畜牧獸醫學會春季學術研討會。台中市。P41. May 17, 2002. 33. 潘居祥、黃天祥、黃金城、王群、鍾明華、林士鈺、劉魯垣、何若澐、張天傑、賴秀穗。2002。應用生物晶片快速診斷豬隻重要病毒性疾病。九十一年度臺灣省畜牧獸醫學會暨中華民國獸醫學會聯合學術研討會。台北市。論文摘要P92。中華民國九十一年十二月十四日。 34. 張天傑。2003。子題一:創新農業科技研發與應用,提升農產品加值效益。第五次全國農業會議。台北市。引言報告P1-9。28-29 March, 2003. 35. 蕭雅如、王孟亮、及張天傑. 2003. 以逆轉錄病毒載體表現豬瘟病毒醣蛋白之研究。九十二年度臺灣省畜牧獸醫學會春季學術研討會。台中市。P56. May 24, 2003. 36. 林克達、王孟亮、及張天傑. 2003. 不同長度之假性狂犬病毒醣蛋白E做為抗體檢測之比較。九十二年度臺灣省畜牧獸醫學會春季學術研討會。台中市。P57. May 24, 2003. 37. Chang, T.-J. 2003. Emerging Diseases of Livestock in Taiwan. International Seminar on Emerging Diseases of Livestock in Asia. Taipei, Taiwan, 10-15 November 2003. 38. Chang, T.-J. 2004. Current status of avian influenza in Taiwan. FAO/OIE Emergency Regional Meeting on Avian Influenza Control in Animals in Asia. Bangkok, Thailand. 26-28 February, 2004. 39. 林惠雯、王孟亮、張元衍、張天傑. 2004. 假性狂犬病毒VHS蛋白缺損之研究。九十三年度臺灣省畜牧獸醫學會春季學術研討會。台中市。P35. May 29, 2004. 40. 林壬威、張元衍、林惠雯、王孟亮、張天傑. 2004. 豬瘟病毒核蛋白對細胞素基因調控之研究. 九十三年度臺灣省畜牧獸醫學會春季學術研討會。台中市。P66. May 29, 2004. 41. 蔡瑀、豐富、張天傑. 2004. 牙齦纖維母細胞、牙周韌帶纖維母細胞以及牙髓腔細胞添加DFDBA之研究. 九十三年度臺灣省畜牧獸醫學會春季學術研討會。台中市。P71. May 29, 2004. 42. Chang, T.-J. 2004. The Current Foot-and-Mouth Disease Prevention and Control Programme of Taipei China. Third OIE Meeting on Foot and Mouth Disease Control in East Asia. Taipei, Taiwan, 30 September – 2 October 2004. 43. 張天傑. 2004. 動物疫苗未來研究之新趨勢. 動物生技產業發展研討會。屏東縣屏東科技大學。October 7-9, 2004. 44. 許茜茹、胡育誠、李龍湖、張天傑、劉宏仁. 2005. 家禽里奧病毒S1133結構蛋白σC單株抗體之製備及特性分析. 九十四年度臺灣省畜牧獸醫學會春季學術研討會。屏東縣。P7. May 14, 2005. 45. 林峰源、王咸祺、張天傑、王孟亮. 2005. 豬第二型環狀病毒Rep蛋白的表現及純化. 九十四年度臺灣省畜牧獸醫學會春季學術研討會。屏東縣。P7. May 14, 2005. 46. 莊為傑、林壬威、張元衍、林惠雯、王群、鍾明華、王孟亮、張天傑. 2005. 豬第二型環狀病毒結構蛋白抗原決定位之研究. 九十四年度臺灣省畜牧獸醫學會春季學術研討會。屏東縣。P7. May 14, 2005. 47. Chang, S.-C., C.-C. Chang, T.-J. Chang and M.-L. Wong. 2005. Prognostic factors associated with survival two years after surgery in dogs with malignant mammary tumors. 九十四年度臺灣省畜牧獸醫學會暨中華民國獸醫學會聯合學術研討會。台中市。論文摘要P82。中華民國九十四年十二月十日。 48. Chang, S.-C., C.-C. Chang, T.-J. Chang and M.-L. Wong. 2005. Role of ovariohysterectomy on dogs after surgical removal of mammary complex carcinomas. 九十四年度臺灣省畜牧獸醫學會暨中華民國獸醫學會聯合學術研討會。台中市。論文摘要P83。中華民國九十四年十二月十日。 49. Shih, H.-C., K.-B. Choo, T.-J. Chang, M.-Y. Yang, M.-C. Shih, K.-T. Yeh, T.-C. Liu, S.-F. Lin and J.-G. Chang. 2005. Circadian gene expression in endometrial cancer detection by real-time PCR. 九十四年度臺灣省畜牧獸醫學會暨中華民國獸醫學會聯合學術研討會。台中市。論文摘要P97。中華民國九十四年十二月十日。 50. Chang, T.-J. 2006. Current FMD Situation and Control Measures. 12th Meeting of the OIE Sub-Commission for FMD in South East Asia, Chiang Mai, Thailand, February 27 to March 3, 2006. 51. 任睿麒、張天傑、徐善慧. 2006. 幾丁聚醣-奈米金複合材料之微溝槽周邊神經導管之修復功能. 九十五年度臺灣省畜牧獸醫學會春季學術研討會。嘉義市。論文摘要第97頁。中華民國九十五年五月十三日。
(C) Other Publications 1.張天傑。如何診治豬的一般疾病。徐氏基金會出版,民國六十九年。 2.Chang, T. J. 1978. A comparison of immune effect of pigs vaccinated with phenol, formalin, and beta-propiolacton inactivated pseudorabies vaccines. M.V.M. Thesis, June 1978, National Taiwan University, ROC. 3.Chang, T. J. 1986. Molecular cloning of bovine viral diarrhea viral genome. Ph.D. Dissertation, September 1986, University of California at Davis, USA. 4.張天傑。RNA病毒基因的分子選殖。1988. 國科會生命科學研究推動中心專刊第十六集,生物技術專題演講論文集(二)第47-55頁。 5.張天傑。1992。病毒性人畜共通傳染病。於獸醫學要覽第一冊:獸醫公共衛生學。第二章第二節,病毒性人畜共通傳染病,第二十一至三十三頁。 6.張天傑。1997。假性狂犬病毒之研究。生命科學簡訊,第十一卷,第十期,10-14頁。 7.張天傑。2001。豬瘟及口蹄疫撲滅計畫專案查證報告。民國九十年十二月。128-180頁。 8.張天傑。2003。疫苗發展之過去、現在、與未來。於動物基因轉植與疫苗發展技術教學資源中心所主編之「疫苗發展技術與實驗」第二章。民國九十二年四月。4-12頁。
獲獎項目:
1.七十六、七十七、七十八、七十九、八十、八十二、八十三、八十四、八十九、及九十年度國科會甲等研究獎。 2.八十一學年度國科會優等研究獎。 3.八十五學年度國科會傑出研究獎(含八十六學年度)。 4.八十六學年度臺灣省畜牧獸醫學會學術獎。 5.八十七學年度國科會傑出研究獎(含八十八學年度)。 6.九十二年台中市特殊績優教師獎。
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